填满和充满的区别主要体现在词义、语境和语法结构上。
首先，词义上的差异：full of 表示主动，常用来描述主语的状态，如“瓶子装满了水”(The bottle is full of water)，强调满的状态。而 fill with 则表示被动，常用于被动语态，如“瓶子被装满了水”(The bottle is filled with water)，重点在于动作的完成。
其次，语境运用有所不同：full of 更适合用于主动句，如“每当我感到难过，游泳后我就会充满能量”(Whenever I feel upset, I would go swimming and then I would be full of energy)。而 full with 常用于被动句，如“医药局费已由一杯牛奶支付”(Paid in full with one glass of milk)。
最后，语法结构上的区别：full of 是副词短语作宾补，补充说明宾语，如“将这本书看作是装满矿石的矿山”(See the book as a mine full of ORE)，而 full with 则是形容词作主补，补充说明主语，如“所有婚后的东西和孩子，都完整地判给我，没有任何附加条件”(All that we owned and built and grew together, including our children, was signed over to me in full with no strings attached)。
