生物统计学中MAF的具体意义是什么?(请详细些)
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发布时间:2022-04-28 11:42
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热心网友
时间:2023-10-07 15:33
是这样的:
对于单核苷酸多态性(SNP),它的次要等位基因频率(MAF)的是单核苷酸多态性的等位基因频率较低在一特定人群中的频率。
想了解更多的话,建议从ncbi上找一些相关的综述来系统学习一下。
For a single-nucleotide polymorphism (SNP), its minor allele frequency (MAF) is the frequency of the SNP's less frequent allele in a given population.
The minor allele frequency (MAF) refers to the frequency at which the less common allele of the SNP occurs in a given population. The lower the minor allele frequency selected, the greater the number of tagSNPs that will be required to represent the variation in a given genomic region.
热心网友
时间:2023-10-07 15:33
是这样的:
对于单核苷酸多态性(SNP),它的次要等位基因频率(MAF)的是单核苷酸多态性的等位基因频率较低在一特定人群中的频率。
想了解更多的话,建议从ncbi上找一些相关的综述来系统学习一下。
For a single-nucleotide polymorphism (SNP), its minor allele frequency (MAF) is the frequency of the SNP's less frequent allele in a given population.
The minor allele frequency (MAF) refers to the frequency at which the less common allele of the SNP occurs in a given population. The lower the minor allele frequency selected, the greater the number of tagSNPs that will be required to represent the variation in a given genomic region.