关于血管正性重构

发布网友 发布时间：2022-04-23 23:46

我来回答

共2个回答

热心网友 时间：2023-10-14 03:22

斑块引起血管内膜发生一系列改变，官腔变小，流速增快，管壁剪切力增大，于是一方面斑块处官壁向外，另一方面血管壁内的胶原会释放一些因子及酶，使其断裂，促使管腔扩张，整体血管增粗，维持剪切力和血流速度回归正常为正性重构
The IVUS vessel remodelling index was calculated
as: [EEM cross-sectional area (CSA) measured at
narrowest lesion site−reference EEM CSA]/
reference EEM CSA×100]. The target lesions were
divided into three groups: group 1 with positive
remodelling (vessel remodelling index >5%), group
2 with negative remodelling (vessel remodelling
index <−5%), and group 3 with intermediate re-
modelling (vessel remodelling index between−5%
and +5%).
参考文献：Prati F, Arbustini E, Labellarte A, Sommariva L, Pawlowski T, Manzoli A, Pagano A, Motolese M, Boccanelli A. Eccentric atherosclerotic plaques with positive remodelling have a pericardial distribution: a permissive role of epicardial fat? A three-dimensional intravascular ultrasound study of left anterior descending artery lesions. Eur Heart J. 2003 Feb;24(4):329-36. doi: 10.1016/s0195-668x(02)00426-8. PMID: 12581680.

热心网友 时间：2023-10-14 03:22

临床上主要应用IVUS来检测冠状动脉重构，其检测方法如下。以距离病变最狭窄处10 mm以内正常且无分支开口的血管为参考血管，测定近远端参考血管的外弹力膜横截面面积（EEM-CSA），计算冠状动脉重构指数（RI）。RI=冠状动脉病变处EEM CSA/近远端参考血管EEM CSA的平均值。通常定义：RI＞1.05，提示正性重构；RI＜0.95，提示负性重构；0.95＜RI＜1.05，提示无重构。